Taraxinic acid is a potent inhibitor of tyrosinase, an enzyme crucial for melanin biosynthesis. Derived from the roots of Taraxacum flavostylum and Taraxacum lucidum, it exhibits a dose-dependent inhibition of tyrosinase activity, achieving approximately 54.5% inhibition at 50 μg/mL. Additionally, Taraxinic acid demonstrates cytotoxic effects against melanoma cell lines A375 and HTB140 with an IC50 of 83.2 μM, and WM793 with an IC50 of 60.4 μM, indicating significant potential for applications in anticancer research.
Taraxinic acid is a potent inhibitor of tyrosinase, an enzyme crucial for melanin biosynthesis. Derived from the roots of Taraxacum flavostylum and Taraxacum lucidum, it exhibits a dose-dependent inhibition of tyrosinase activity, achieving approximately 54.5% inhibition at 50 μg/mL. Additionally, Taraxinic acid demonstrates cytotoxic effects against melanoma cell lines A375 and HTB140 with an IC50 of 83.2 μM, and WM793 with an IC50 of 60.4 μM, indicating significant potential for applications in anticancer research.
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