TAS-115 mesylate

Catalog No.: A21389

c-Met/HGFR inhibitor

TAS-115 mesylate

TAS-115 mesylate Chemical Structure

CAS NO. 1688673-09-7

TAS-115 mesylate is a potent VEGFRand hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor, with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $585.00

Special Price $468.00

10 mg

Regular Price: $1,008.00

Special Price $806.40

50 mg

Regular Price: $2,990.00

Special Price $2,392.00

100 mg

Regular Price: $5,980.00

Special Price $4,784.00

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Biological Activity

TAS-115 mesylate is a potent VEGFRand hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor, with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.27 mL 81.35 mL 162.69 mL
0.5 mM 3.25 mL 16.27 mL 32.54 mL
1 mM 1.63 mL 8.13 mL 16.27 mL
5 mM 0.33 mL 1.63 mL 3.25 mL

*The above data is based on the productmolecular weight 614.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21389
Actions Inhibitor
CAS No. 1688673-09-7
Formula C28H27FN4O7S2
M. Wt 614.66
Purity >98%
Synonyms TAS-115 methanesulfonate, TAS115, TAS 115
SMILES CS(=O)(O)=O.O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC(CC4=CC=CC=C4)=O)=S)C=C3F)C2=C1)NC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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