TAS-115

Catalog No.: A21533

VEGFR/c-Met/HGFR inhibitor

TAS-115

TAS-115 Chemical Structure

CAS NO. 1190836-34-0

TAS-115 is a potent VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $1,382.00

Special Price $1,105.60

5 mg

Regular Price: $4,147.00

Special Price $3,317.60

10 mg

Regular Price: $7,066.00

Special Price $5,652.80

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TAS-115 is a potent VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase inhibitor with IC50s of 30 and 32 nM for rVEGFR2 and rMET, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.42 mL 192.84 mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21533
Actions Inhibitor
CAS No. 1190836-34-0
Formula C27H23FN4O4S
M. Wt 518.56
Purity >98%
Synonyms TAS-115, TAS115, TAS 115
SMILES O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC(CC4=CC=CC=C4)=O)=S)C=C3F)C2=C1)NC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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