Tau Ligand-1 is a specific ligand that targets aggregated tau protein and is capable of crossing the blood-brain barrier. Demonstrating high affinity for aggregated tau in brain tissues from Alzheimer's disease and other tauopathies, it displays equilibrium dissociation constant (KD) values between 1 and 3.8 nM. This compound shows potential as a positron emission tomography (PET) tracer, offering valuable applications in imaging studies related to tau-associated neurodegenerative diseases in the central nervous system.
Tau Ligand-1 is a specific ligand that targets aggregated tau protein and is capable of crossing the blood-brain barrier. Demonstrating high affinity for aggregated tau in brain tissues from Alzheimer's disease and other tauopathies, it displays equilibrium dissociation constant (KD) values between 1 and 3.8 nM. This compound shows potential as a positron emission tomography (PET) tracer, offering valuable applications in imaging studies related to tau-associated neurodegenerative diseases in the central nervous system.
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