Fig. 1 · Structure
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Tavapadon
Dopamine D1/D5 Receptor Agonist
Tavapadon is a selective partial agonist of the dopamine D1 and D5 receptors. This orally active compound demonstrates significant efficacy in promoting motor function and alleviating disability, making it a promising candidate for research into Parkinson’s disease therapies. Tavapadon’s unique pharmacological profile supports its potential application in neurologic studies and drug development aimed at addressing dopamine-related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 1643489-24-0 |
| Applications | Dopamine D1/D5 Receptor Agonist |
| Formula | C19H16F3N3O3 |
| Molecular Weight | 391.34 |
| Synonyms | PF-06649751; CVL-751 |
| SMILES | O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.