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CK2 Inhibitor

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Catalog No. A15257

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TBB 10mg A15257-10
TBB 25mg A15257-25
TBB 50mg A15257-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 uM for rat liver and human recombinant CK2 respectively).


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Chemical Information

Catalog Num A15257
Actions Inhibitor
M. Wt 434.71
Formula C6HBr4N3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 17374-26-4
Synonyms NSC 231634, TBB (enzyme inhibitor), 1H-Benzotriazole, 4,5,6,7-tetrabromo-
SMILES code C1(=C(C2=NNN=C2C(=C1Br)Br)Br)Br
Chemical Name 4,5,6,7-tetrabromo-2H-benzotriazole

Biological Activity

TBB is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2)with IC50s of 0.9 and 1.6 uM for rat liver and human recombinant CK2 respectively).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23 mL 115.02 mL 230.04mL
0.5 mM 4.6 mL 23 mL 46.01 mL
1 mM 2.3 mL 11.5 mL 23 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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