Fig. 1 · Structure
Documents & Downloads
TBDMS-PEG4-OH
PROTAC Linker
TBDMS-PEG4-OH is a PEG4-based PROTAC linker designed to facilitate the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the synthesis of PROTACs by connecting a target ligand to an E3 ligase, enhancing targeted protein degradation. Its unique structure allows for increased solubility and flexibility, making it ideal for various applications in chemical biology and drug discovery research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 134179-40-1 |
| Applications | PROTAC Linker |
| Formula | C14H32O5Si |
| Molecular Weight | 308.49 |
| SMILES | CC(C)([Si](C)(OCCOCCOCCOCCO)C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.