Fig. 1 · Structure
Documents & Downloads
TBK1/IKKε-IN-1
Cat. No.
A79491
CAS
2058264-32-5
IKK Inhibitor
TBK1/IKKε-IN-1 is a potent dual inhibitor of TBK1 and IKKε, demonstrating IC50 values of less than 100 nM. This compound is valuable for research applications involving the modulation of inflammatory pathways and immune responses. Its inhibition of these kinases provides a tool for studying their roles in various biological processes and disease states, particularly those related to cancer and neuroinflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2058264-32-5 |
| Applications | IKK Inhibitor |
| Formula | C28H26N4O5 |
| Molecular Weight | 498.53 |
| SMILES | O=C(C1=CC(OC)=C(C2=CC3=NC=CC(C4=CC=C(OC5CCOCC5)C(C#N)=C4)=C3O2)N=C1)N(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.