Fig. 1 · Structure
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TBK1/IKKε-IN-6
Cat. No.
A79476
CAS
2306877-20-1
TBK1 and IKKε Inhibitor
TBK1/IKKε-IN-6 is a selective inhibitor of TBK1 and IKKε, exhibiting IC50 values below 100 nM for both targets. This compound plays a significant role in modulating inflammatory signaling pathways by inhibiting the activation of these kinases. It is particularly useful in research focused on autoimmune diseases, cancer, and viral infections, enabling the exploration of therapeutic strategies targeting the TBK1/IKKε pathway.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2306877-20-1 |
| Applications | TBK1 and IKKε Inhibitor |
| Formula | C31H36F2N8O4 |
| Molecular Weight | 622.67 |
| SMILES | COC1=C(N2[C@@H](CN(CC2)C)C)C=CC(NC3=NC=CC(C4=CC(C#N)=C(C=C4)OC5C(F)(CN(CC5)C([C@H](O)C)=O)F)=N3)=N1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.