Fig. 1 · Structure

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TBK1 ligand 2

TBK1 Ligand

TBK1 Ligand 2 is a selective inhibitor of TBK1, a kinase involved in cellular stress response and inflammation. This compound facilitates the synthesis of PROTAC TBK1 degrader-2, providing a valuable tool for research into targeted protein degradation and the modulation of TBK1-associated pathways. TBK1 Ligand 2 may aid in the investigation of its roles in various diseases, including cancer and neurodegenerative disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2052306-16-6
Applications TBK1 Ligand
Formula C21H28BrN5O2
Molecular Weight 462.38
SMILES
O=C(C1CCC1)N(CCCNC2=NC(NC3=CC=C(C=C3)OCC)=NC=C2Br)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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