Fig. 1 · Structure
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TCEP-biotin
Crotonylation probe
TCEP-biotin is a biotinylated derivative of tris(2-carboxyethyl)phosphine (TCEP) that serves as a specific probe for histone lysine crotonylation. This reagent enables the detection and study of crotonylation modifications on histones, providing valuable insights into epigenetic regulation and its implications in various biological processes. It is a useful tool for researchers investigating post-translational modifications and their roles in gene expression and chromatin dynamics.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2227020-26-8 |
| Applications | Crotonylation probe |
| Formula | C25H43N4O9PS |
| Molecular Weight | 606.67 |
| Synonyms | Tris(2-carboxyethyl)phosphine-biotin |
| SMILES | OC(CCP(CCC(O)=O)CCC(NCCOCCOCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.