Fig. 1 · Structure

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TCEP hydrochloride

Non-Thiol Reducing Agent

TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that effectively reduces protein disulfide bonds without disrupting thiol-targeted processes. Its high stability and rapid reduction capability make TCEP hydrochloride an ideal choice for various biochemical applications. It is widely utilized in protein chemistry, particularly in the preparation of samples for assays and in DNA/gold nanoparticle conjugation studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 51805-45-9
Applications Non-Thiol Reducing Agent
Formula C9H16ClO6P
Molecular Weight 286.65
Synonyms Tris(2-​carboxyethyl)​phosphine hydrochloride
SMILES
O=C(O)CCP(CCC(O)=O)CCC(O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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