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TcO-ABX474

Catalog No.: A65445
PSMA Inhibitor
TcO-ABX474 is a potent inhibitor of prostate-specific membrane antigen (PSMA), exhibiting a Kd value of 6.1 nM. It effectively inhibits the growth and metastasis of prostate cancer cells, making it a valuable tool for research in prostate cancer biology. This compound is suitable for studies investigating PSMA-mediated pathways and the development of targeted therapies for prostate cancer.
TcO-ABX474 3019987-06-2 PSMA Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTcO-ABX474 is a potent inhibitor of prostate-specific membrane antigen (PSMA), exhibiting a Kd value of 6.1 nM. It effectively inhibits the growth and metastasis of prostate cancer cells, making it a valuable tool for research in prostate cancer biology. This compound is suitable for studies investigating PSMA-mediated pathways and the development of targeted therapies for prostate cancer.
Product Information
Catalog NumA65445
FormulaC51H86N9O19S2Tc
Molecular Weight1292.31
CAS Number3019987-06-2
SMILESO=C(CC[C@H](C(O)=O)NC(N[C@@H](C(O)=O)CCCCNC(CCCCCCC(NCCCC[C@H](NC([C@H](NC([C@@H](NC(CCCC[N]1(CC(C)(C)S2)CCN(CC(C)(C)S3)[Tc]132=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)C(O)=O)=O)=O)=O)O
SynonymsTcO-5
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