Biological Activity
TCPOBOP is an agonist of the constitutive androstane receptor (CAR) (EC50 = 20 nM). TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.87 mL | 124.36 mL | 248.73 mL |
0.5 mM | 4.97 mL | 24.87 mL | 49.75 mL |
1 mM | 2.49 mL | 12.44 mL | 24.87 mL |
5 mM | 0.5 mL | 2.49 mL | 4.97 mL |
*The above data is based on the productmolecular weight 402.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18376 |
---|---|
Actions | Agonist |
CAS No. | 76150-91-9 |
Formula | C16H8Cl4N2O2 |
M. Wt | 402.05 |
Solubility | DMSO |
Purity | >98% |
Synonyms | TCPOBOP |
SMILES | ClC1=CN=C(OC2=CC=C(OC3=NC=C(Cl)C=C3Cl)C=C2)C(Cl)=C1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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