TCS 401 free base

Catalog No.: A15390

PTP1B Inhibitor

TCS 401 free base

TCS 401 free base Chemical Structure

CAS NO. 243967-42-2

TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) (Ki values are 0.29, 59, 560, 1100, > 2000, > 2000 and > 2000 μM for PTP1B, CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2 respectively).

Availability: In stock

Package Price Qty
10 mg
$164.00
25 mg
$320.00
50 mg
$695.00
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Biological Activity

TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) (Ki values are 0.29, 59, 560, 1100, > 2000, > 2000 and > 2000 μM for PTP1B, CD45 D1D2, PTPβ, PTPε D1, SHP-1, PTPα D1 and LAR D1D2 respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37 mL 185.01 mL 370.01 mL
0.5 mM 7.4 mL 37 mL 74 mL
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15390
Actions Inhibitor
M. Wt 270.26
Formula C10H10N2O5S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 243967-42-2
Synonyms TCS401, TCS-401
SMILES O=C(C1=C(NC(C(O)=O)=O)SC2=C1CCNC2)O

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