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TEAD-IN-22

TEAD Inhibitor

TEAD-IN-22 is a potent TEAD inhibitor, targeting the transcriptional co-activators of the Hippo signaling pathway. This compound exhibits significant anti-cancer and anti-fibrotic activities, making it a valuable tool for researchers studying tumorigenesis and fibrotic diseases. Its inhibitory effects on TEAD-mediated transcription provide insights into cellular processes and disease mechanisms associated with dysregulated Hippo signaling.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3034813-65-2
Applications	TEAD Inhibitor
Formula	C₂₂H₂₀F₃N₃O₃
Molecular Weight	431.41
SMILES	OC(C1)CN1C([C@H]2[C@H](C3=CC(OC4=CC=C(C(F)(F)F)C=C4)=CC5=CN(C)N=C35)C2)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.