Fig. 1 · Structure

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TEAD-IN-24

TEAD Inhibitor

TEAD-IN-24 is a potent TEAD inhibitor that targets the TEA domain transcription factors. This compound demonstrates significant anti-cancer activity, particularly in non-small cell lung cancer models. It serves as a valuable tool for research investigating the role of TEAD in tumor progression and therapeutic resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 3034813-75-4
Applications TEAD Inhibitor
Formula C23H22F3N3O4
Molecular Weight 461.43
SMILES
O=C(N1C[C@H]([C@@H](C1)O)O)C2C(C(C3=N4)=CC(OC5=CC=C(C=C5)C(F)(F)F)=CC3=CN4C)C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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