Fig. 1 · Structure
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TEAD-IN-6
TEAD Modulator
TEAD-IN-6 is a TEAD modulator that inhibits the interaction between YAP1/TAZ and the TEAD transcription factor. This compound plays a significant role in cancer research by elucidating the mechanistic pathways associated with TEAD-mediated gene expression. Its ability to disrupt this interaction makes it a valuable tool for studying the oncogenic activities of YAP1/TAZ in various cancer models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 2821763-12-4 |
| Applications | TEAD Modulator |
| Formula | C19H17F3N4O3S |
| Molecular Weight | 438.42 |
| SMILES | O=S(C1=CC(C2=CN3C(CCC3)=N2)=C(OC4=CC=C(C(F)(F)F)C=C4)N=C1)(NC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.