Fig. 1 · Structure

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Tebanicline dihydrochloride

nAChR Agonist

Tebanicline dihydrochloride is a selective agonist of nicotinic acetylcholine receptors (nAChRs), particularly targeting the α4β2 subtype. It exhibits strong analgesic properties and demonstrates oral bioavailability. This compound is valuable for research into pain management and the modulation of cholinergic signaling in neurological studies.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 209326-19-2
Applications nAChR Agonist
Formula C9H13Cl3N2O
Molecular Weight 271.57
Synonyms Ebanicline dihydrochloride; ABT-594 dihydrochloride
SMILES
[H]Cl.ClC(C=C1)=NC=C1OC[C@@H]2NCC2.[H]Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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