Fig. 1 · Structure

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Tebanicline

Neuronal Nicotinic Acetylcholine Receptor Agonist

Tebanicline is a potent agonist of neuronal nicotinic acetylcholine receptors, specifically exhibiting high affinity for the α4β2 subunit in the central nervous system. This compound demonstrates significant antinociceptive effects, making it valuable for research in pain modulation and neurological studies. Its selective action on nicotinic receptors positions tebanticline as an important tool for exploring receptor function and therapeutic applications in neurobiology.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 198283-73-7
Applications Neuronal Nicotinic Acetylcholine Receptor Agonist
Formula C9H11ClN2O
Molecular Weight 198.65
Synonyms Ebanicline; ABT-594
SMILES
ClC(C=C1)=NC=C1OC[C@@H]2NCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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