Tegoprazan

Catalog No.: A20873

gastric H+/K+-ATPase inhibitor

Tegoprazan

Tegoprazan Chemical Structure

CAS NO. 942195-55-3

Tegoprazan, a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Tegoprazan, a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.81 mL 129.07 mL 258.14 mL
0.5 mM 5.16 mL 25.81 mL 51.63 mL
1 mM 2.58 mL 12.91 mL 25.81 mL
5 mM 0.52 mL 2.58 mL 5.16 mL

*The above data is based on the productmolecular weight 387.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20873
Actions Inhibitor
M. Wt 387.38
Formula C20H19F2N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 942195-55-3
SMILES FC1=CC(F)=C2[[email protected]@H](OC3=CC(C(N(C)C)=O)=CC4=C3N=C(C)N4)CCOC2=C1

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