Fig. 1 · Structure
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Tempone
Metabolically Active Contrast Agent
Tempone (4-Oxo-Tempo) functions as a stable, water-soluble nitroxide radical and serves as a metabolically active contrast agent. Its primary applications include enhancing metabolic activity and assessing hypoxic sensitivity through electron spin resonance spectroscopy, magnetic resonance imaging, and dynamic nuclear polarization. Tempone exhibits superoxide dismutase (SOD)-mimetic activity, effectively reducing superoxide radicals and limiting the production of hydroxyl radicals and peroxynitrites. This compound is valuable in investigations of ischemia-reperfusion injury and acute renal failure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2896-70-0 |
| Applications | Metabolically Active Contrast Agent |
| Formula | C9H16NO2* |
| Molecular Weight | 170.23 |
| Synonyms | 4-Oxo-Tempo |
| SMILES | [O]N1C(C)(C)CC(CC1(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.