Teriflunomide

Catalog No.: A18052
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Grouped product items
Product Name Price Stock Qty
Teriflunomide 50mg
$63.00
In stock
Teriflunomide 100mg
$109.00
In stock
Teriflunomide 500mg
$322.00
In stock

Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Chemical Information
Catalog Num A18052
Formula C12H9F3N2O2
Molecular Weight 270.21
CAS Number 163451-81-8
SMILES C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O.[(Z)]
Synonyms A77 1726, A77-1726
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 28 mg/mL (103.62 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.01 mL 185.04 mL 370.08 mL
0.5 mM 7.4 mL 37.01 mL 74.02 mL
1 mM 3.7 mL 18.5 mL 37.01 mL
5 mM 0.74 mL 3.7 mL 7.4 mL
Useful Calculator

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