Fig. 1 · Structure

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tert-Butyl 2,8-diazaspiro4.5decane-2-carboxylate hydrochloride

PROTAC Linker

tert-Butyl 2,8-diazaspiro[4.5]decane-2-carboxylate hydrochloride serves as a PROTAC linker facilitating the development of PROTACs for targeted protein degradation. This compound exhibits robust stability and solubility, making it ideal for diverse applications in drug discovery. It is particularly useful for the design and synthesis of molecules aimed at selectively modulating protein levels, thereby advancing therapeutic research in various diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 869976-20-5
Applications PROTAC Linker
Formula C13H25ClN2O2
Molecular Weight 276.81
SMILES
Cl.O=C(OC(C)(C)C)N1CCC2(C1)CCNCC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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