Fig. 1 · Structure
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tert-Butyl 2-(piperidin-4-yl)acetate
PROTAC Linker
tert-Butyl 2-(piperidin-4-yl)acetate serves as an efficient PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the targeted degradation of proteins by linking E3 ligases with the proteins of interest, enabling precise modulation of cellular pathways. Its applications are crucial in drug discovery and development, particularly for studying protein interactions and cellular functions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 180182-07-4 |
| Applications | PROTAC Linker |
| Formula | C11H21NO2 |
| Molecular Weight | 199.29 |
| SMILES | O=C(OC(C)(C)C)CC1CCNCC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.