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tert-Butyl 3,3'-biazetidine-1-carboxylate hydrochloride

PROTAC Linker

tert-Butyl [3,3'-biazetidine]-1-carboxylate hydrochloride is a specialized linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of specific proteins within cells by linking E3 ligases to substrates. Its robust chemical properties make it suitable for various applications in protein degradation research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2007910-70-3
Applications	PROTAC Linker
Formula	C₁₁H₂₁ClN₂O₂
Molecular Weight	248.75
SMILES	Cl.O=C(OC(C)(C)C)N1CC(C1)C2CNC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.