tert-Butyl 3,3'-biazetidine-1-carboxylate hydrochloride

Catalog No.: A84042
PROTAC Linker
tert-Butyl [3,3'-biazetidine]-1-carboxylate hydrochloride is a specialized linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of specific proteins within cells by linking E3 ligases to substrates. Its robust chemical properties make it suitable for various applications in protein degradation research and therapeutic development.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptiontert-Butyl [3,3'-biazetidine]-1-carboxylate hydrochloride is a specialized linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of specific proteins within cells by linking E3 ligases to substrates. Its robust chemical properties make it suitable for various applications in protein degradation research and therapeutic development.
Product Information
Catalog NumA84042
FormulaC11H21ClN2O2
Molecular Weight248.75
CAS Number2007910-70-3
SMILESCl.O=C(OC(C)(C)C)N1CC(C1)C2CNC2
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