Fig. 1 · Structure
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tert-Butyl 3-hydroxypropanoate
PROTAC Linker
tert-Butyl 3-hydroxypropanoate functions as a crucial PROTAC linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates targeted protein degradation by connecting an E3 ligase ligand with a target protein ligand, thus enhancing the efficacy of bifunctional molecules in research applications. Its unique structural properties make it suitable for developing novel therapeutic strategies aimed at selectively degrading disease-causing proteins.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 59854-11-4 |
| Applications | PROTAC Linker |
| Formula | C7H14O3 |
| Molecular Weight | 146.19 |
| SMILES | O=C(OC(C)(C)C)CCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.