Fig. 1 · Structure
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tert-Butyl 6-bromohexanoate
PROTAC Linker
tert-Butyl 6-bromohexanoate serves as a PROTAC linker, facilitating the targeted degradation of specific proteins. This compound can be utilized in the design of PROTACs, such as the PROTAC ERK5 degrader-1, to enhance selective protein removal for research in cellular biology and therapeutic applications. Its structural attributes support efficient conjugation and functionalization for effective protein degradation studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 65868-63-5 |
| Applications | PROTAC Linker |
| Formula | C10H19BrO2 |
| Molecular Weight | 251.16 |
| SMILES | O=C(OC(C)(C)C)CCCCCBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.