Fig. 1 · Structure
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tert-Butyl 8-bromooctanoate
PROTAC Linker
tert-Butyl 8-bromooctanoate serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins, thereby advancing research in targeted protein degradation and therapeutic development. Its structural properties support the formation of robust linkages, making it a valuable tool for researchers investigating novel protein modulation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 77383-17-6 |
| Applications | PROTAC Linker |
| Formula | C12H23BrO2 |
| Molecular Weight | 279.22 |
| SMILES | O=C(OC(C)(C)C)CCCCCCCBr |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.