Fig. 1 · Structure
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tert-Butyl 8-hydroxyoctanoate
PROTAC Linker
Tert-Butyl 8-hydroxyoctanoate functions as a PROTAC linker, facilitating the synthesis of various PROTACs, including PROTAC CDK Degrader-1. This compound exhibits potent anti-tumor activity through targeted degradation of cyclin-dependent kinases (CDKs), making it a valuable tool for cancer research and therapeutic development. Its role in PROTAC design enhances the specificity and efficacy of targeted protein degradation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 401901-41-5 |
| Applications | PROTAC Linker |
| Formula | C12H24O3 |
| Molecular Weight | 216.32 |
| SMILES | O=C(OC(C)(C)C)CCCCCCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.