Fig. 1 · Structure
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tert-Butyl 9-oxo-3-azaspiro5.5undecane-3-carboxylate
PROTAC Linker
tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate serves as an efficient PROTAC linker, facilitating the development of targeted protein degradation agents. This compound enhances the molecular interactions necessary for the effective recruitment of E3 ligases, thereby promoting the ubiquitination and subsequent degradation of specific target proteins. Its application is pivotal in research focused on developing therapeutic strategies that harness the power of the ubiquitin-proteasome system for selective protein manipulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 873924-08-4 |
| Applications | PROTAC Linker |
| Formula | C15H25NO3 |
| Molecular Weight | 267.37 |
| SMILES | O=C(OC(C)(C)C)N1CCC2(CCC(=O)CC2)CC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.