Fig. 1 · Structure

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tert-Butyl but-3-yn-1-ylcarbamate

PROTAC Linker

tert-Butyl but-3-yn-1-ylcarbamate serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins, making it a valuable reagent in drug discovery and protein research applications. Its unique structure allows for improved conjugation efficiency and stability in various biochemical contexts.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 149990-27-2
Applications PROTAC Linker
Formula C9H15NO2
Molecular Weight 169.22
SMILES
O=C(OC(C)(C)C)NCCC#C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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