Fig. 1 · Structure

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tert-Butyl cis-4-(hydroxymethyl)cyclohexylcarbamate

PROTAC Linker

tert-Butyl cis-4-(hydroxymethyl)cyclohexylcarbamate functions as a versatile PROTAC linker, facilitating the development of bifunctional molecules that induce proteolysis of target proteins. Its structural features enhance target specificity and enable effective recruitment of E3 ligases. This compound is instrumental in proteomics research, aiding in targeted protein degradation studies and drug discovery applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 223131-01-9
Applications PROTAC Linker
Formula C12H23NO3
Molecular Weight 229.32
SMILES
N(C(OC(C)(C)C)=O)[C@H]1CC[C@@H](CO)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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