Fig. 1 · Structure
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tert-Butyl hex-5-yn-1-ylcarbamate
PROTAC Linker
tert-Butyl hex-5-yn-1-ylcarbamate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) in chemical biology research. By linking an E3 ligase ligand and a target protein binder, this compound enhances the targeted degradation of specific proteins, making it a valuable tool for studying protein functions and cellular processes. Its chemical properties support efficient synthesis and application in various research settings focused on protein modulation and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 151978-58-4 |
| Applications | PROTAC Linker |
| Formula | C11H19NO2 |
| Molecular Weight | 197.28 |
| SMILES | O=C(OC(C)(C)C)NCCCCC#C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.