Fig. 1 · Structure

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tert-Butyl N-{2-azaspiro4.5decan-8-yl}carbamate

PROTAC Linker

tert-Butyl N-{2-azaspiro[4.5]decan-8-yl}carbamate serves as a linker in the assembly of PROTACs (Proteolysis Targeting Chimeras). This compound plays a crucial role in the design of bifunctional molecules that modulate protein degradation pathways. It supports research in targeted protein degradation, a promising approach for therapeutic intervention in various diseases, including cancer.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1341038-05-8
Applications PROTAC Linker
Formula C14H26N2O2
Molecular Weight 254.37
SMILES
O=C(OC(C)(C)C)NC1CCC2(CNCC2)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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