Fig. 1 · Structure
Documents & Downloads
tert-Butyl N-3-(piperazin-1-yl)propylcarbamate
PROTAC Linker
tert-Butyl N-[3-(piperazin-1-yl)propyl]carbamate serves as a versatile linker in the synthesis of PROTAC (Proteolysis Targeting Chimeras) compounds. This compound is particularly utilized in the development of the PROTAC degrader TrimTAC1, facilitating targeted protein degradation through the recruitment of E3 ligases. Its application in chemical biology enables researchers to investigate protein function and modulation in various biological pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 874831-60-4 |
| Applications | PROTAC Linker |
| Formula | C12H25N3O2 |
| Molecular Weight | 243.35 |
| SMILES | O=C(NCCCN1CCNCC1)OC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.