Fig. 1 · Structure
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tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamate
PROTAC Linker
tert-Butyl (trans-3-(methylamino)cyclobutyl)carbamate is a chemical linker specifically designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the formation of bifunctional molecules that simultaneously engage a target protein and the ubiquitin-proteasome system, promoting targeted degradation. Its applications are vital in the development of novel therapeutic strategies for various diseases, including cancer and neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2168236-44-8 |
| Applications | PROTAC Linker |
| Formula | C10H20N2O2 |
| Molecular Weight | 200.28 |
| SMILES | N(C(OC(C)(C)C)=O)[C@H]1C[C@H](NC)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.