Fig. 1 · Structure

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tert-Butyl trans-4-aminocyclohexanecarboxylate

PROTAC Linker

tert-Butyl trans-4-aminocyclohexanecarboxylate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This reagent is essential for linking target proteins to E3 ligases, enabling the targeted degradation of intracellular proteins. Its application is pivotal in drug discovery and biochemical research, particularly in exploring therapeutic strategies for diseases where protein misregulation occurs.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1022159-15-4
Applications PROTAC Linker
Formula C11H21NO2
Molecular Weight 199.29
SMILES
C(OC(C)(C)C)(=O)[C@H]1CC[C@H](N)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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