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Tesidolumab
Tesidolumab (LFG316) is a fully human IgG1/λ monoclonal antibody with a molecular weight of 143 kDa in its non-glycosylated form. This antibody specifically targets and binds to complement component 5 (C5), effectively inhibiting its cleavage and the subsequent formation of the membrane attack complex (MAC). This blockade is crucial in preventing the cascade of events that lead to cell lysis and inflammation, making Tesidolumab a valuable tool for research into complement-mediated diseases and therapeutic interventions.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1531594-08-7 |
| Molecular Weight | 145500 |
| Synonyms | LFG316; Anti-Human C5 Recombinant Antibody |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.