Fig. 1 · Structure
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(-)-Tetrabenazine ((3S,11bS)-TBZ)
Cat. No.
A67454
CAS
1026016-84-1
VMAT2 Inhibitor
(-)-Tetrabenazine is a specific inhibitor of the vesicular monoamine transporter 2 (VMAT2). This compound exhibits notable biological activity in the modulation of monoamine neurotransmitter levels, making it valuable for research in neuropharmacology and the study of movement disorders. Its role as a VMAT2 inhibitor can aid in the investigation of drug development for conditions such as Huntington's disease and other neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1026016-84-1 |
| Applications | VMAT2 Inhibitor |
| Formula | C19H27NO3 |
| Molecular Weight | 317.42 |
| Synonyms | (-)-TBZ; (3S,11bS)-TBZ; (3S,11bS)-Tetrabenazine |
| SMILES | COC1=C(OC)C=C2CCN(C[C@@H](C(C3)=O)CC(C)C)[C@]3([H])C2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.