Fig. 1 · Structure
Documents & Downloads
Tetradifon
Organochlorine Insecticide
Tetradifon, an organochlorine insecticide, primarily targets the mitochondrial oligomycin sensitivity conferring protein (OSCP). It demonstrates broad-spectrum activity against various mite species and effectively inhibits energy-related processes, including ADP-stimulated respiration and ATPase activity, with an IC50 of 4.5-27 nM/mg mitochondrial protein. Tetradifon's mode of action involves the disruption of oxidative phosphorylation, leading to oxidative stress and potential interference with bone metabolism. This compound is utilized in research focused on mitochondrial function regulation, bone remodeling mechanisms, and the nephrotoxic effects of environmental pollutants.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 116-29-0 |
| Applications | Organochlorine Insecticide |
| Formula | C12H6Cl4O2S |
| Molecular Weight | 356.05 |
| SMILES | O=S(C1=C(C=C(C(Cl)=C1)Cl)Cl)(C2=CC=C(C=C2)Cl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.