Fig. 1 · Structure
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Tetraethylene glycol monomethyl ether
PROTAC Linker
Tetraethylene glycol monomethyl ether is a polyethylene glycol (PEG)-based linker specifically designed for use in PROTAC (proteolysis-targeting chimeras) synthesis. This versatile reagent facilitates the assembly of PROTACs by enhancing solubility and stability, thereby improving their pharmacological profiles. It is widely utilized in research applications aimed at targeted protein degradation, contributing to advancements in drug discovery and development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 23783-42-8 |
| Applications | PROTAC Linker |
| Formula | C9H20O5 |
| Molecular Weight | 208.25 |
| SMILES | COCCOCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.