Fig. 1 · Structure
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Tetrahydropyranyldiethyleneglycol
PROTAC Linkers
Tetrahydropyranyldiethyleneglycol is a PEG-based PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the creation of bifunctional molecules that efficiently induce targeted degradation of specific proteins, enabling researchers to investigate protein function and therapeutic interventions. It is an essential tool in drug discovery and development, particularly for studies focused on targeted protein degradation pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2163-11-3 |
| Applications | PROTAC Linkers |
| Formula | C9H18O4 |
| Molecular Weight | 190.24 |
| Synonyms | THP-PEG2-OH |
| SMILES | OCCOCCOC1CCCCO1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.