TF-S14 is a reverse agonist of RORγt, a transcription factor critically involved in Th17 cell differentiation and cytokine production. By binding to RORγt, TF-S14 effectively inhibits the secretion of pro-inflammatory cytokines such as IL-17A, IL-21, and IL-22. This compound is valuable for research applications focused on autoimmune diseases and transplantation rejection mechanisms.
TF-S14 is a reverse agonist of RORγt, a transcription factor critically involved in Th17 cell differentiation and cytokine production. By binding to RORγt, TF-S14 effectively inhibits the secretion of pro-inflammatory cytokines such as IL-17A, IL-21, and IL-22. This compound is valuable for research applications focused on autoimmune diseases and transplantation rejection mechanisms.
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