TFLLR-NH2(TFA)

Catalog No.: A63463
PAR1 Agonist
TFLLR-NH2 (TFA) is a selective agonist of the Protease-Activated Receptor-1 (PAR1), exhibiting an EC50 of 1.9 μM. It effectively activates PAR1-mediated signaling pathways, making it a valuable tool for investigating thrombin-related physiological processes. This compound is suitable for research applications in vascular biology, platelet function studies, and the exploration of cardiovascular disease mechanisms.
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
5mg
$125.00
In stock
10mg
$200.00
In stock
25mg
$360.00
In stock
50mg
$535.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTFLLR-NH2 (TFA) is a selective agonist of the Protease-Activated Receptor-1 (PAR1), exhibiting an EC50 of 1.9 μM. It effectively activates PAR1-mediated signaling pathways, making it a valuable tool for investigating thrombin-related physiological processes. This compound is suitable for research applications in vascular biology, platelet function studies, and the exploration of cardiovascular disease mechanisms.
Product Information
Catalog NumA63463
FormulaC33H54F3N9O8
Molecular Weight761.83
CAS Number1313730-19-6
Sequence shorteningTFLLR-NH2
SMILESOC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2