TG11-77 hydrochloride is a highly selective antagonist of the EP2 receptor, demonstrating potent inhibition with a KB value of 9.7 nM. This compound effectively blocks PGE2-induced activation of the human EP2 receptor, leading to significant anti-inflammatory effects. TG11-77 hydrochloride has also been shown to reduce delayed mortality and mitigate memory deficits, making it a valuable tool for research in neuroinflammation and related therapeutic areas.
TG11-77 hydrochloride is a highly selective antagonist of the EP2 receptor, demonstrating potent inhibition with a KB value of 9.7 nM. This compound effectively blocks PGE2-induced activation of the human EP2 receptor, leading to significant anti-inflammatory effects. TG11-77 hydrochloride has also been shown to reduce delayed mortality and mitigate memory deficits, making it a valuable tool for research in neuroinflammation and related therapeutic areas.
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