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TGF-β1/Smad-IN-1

TGF-β1/Smad Inhbitor

TGF-β1/Smad-IN-1 is a potent inhibitor of the TGF-β1/Smad signaling pathway, which plays a crucial role in the regulation of fibrotic processes. This compound effectively reduces the expression of fibrosis markers, such as α-SMA and COL1A1, induced by TGF-β1, demonstrating significant antifibrotic activity. TGF-β1/Smad-IN-1 is valuable for research applications focused on hepatic fibrosis and related fibrotic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3097194-50-5
Applications	TGF-β1/Smad Inhbitor
Formula	C₁₈H₁₉ClN₂O₆
Molecular Weight	394.81
SMILES	ClC(C=C1NCC2=CC[C@@]3([H])[C@]2([H])[C@H](OC)OC=C3C(OC)=O)=C(C=C1)[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.