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Biological Activity
TGFβRI-IN-1 is an oral active and selective TGFβ receptor type I (TGFβRI) kinase inhibitor, with IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.59 mL | 137.97 mL | 275.94 mL |
| 0.5 mM | 5.52 mL | 27.59 mL | 55.19 mL |
| 1 mM | 2.76 mL | 13.8 mL | 27.59 mL |
| 5 mM | 0.55 mL | 2.76 mL | 5.52 mL |
*The above data is based on the productmolecular weight 362.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18800 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1950628-94-0 |
| Formula | C20H14D3N5O2 |
| M. Wt | 362.4 |
| Purity | >98% |
| SMILES | CC(NC1=NC=CC(C(N2)=C(C3=NC=C(OC([2H])([2H])[2H])C=C3)C4=C2C=CC=N4)=C1)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
United StatesAdooq Bioscience
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