TGFβ-IN-3 is a prodrug that selectively inhibits TGFβR1. It exhibits enhanced selective drug release within tumors, resulting in a significant 2.2-fold increase in the tumor-to-blood concentration ratio. This compound is valuable for researching colon cancer and its associated signaling pathways, providing insights into potential therapeutic strategies targeting the TGFβ axis in tumor microenvironments.
TGFβ-IN-3 is a prodrug that selectively inhibits TGFβR1. It exhibits enhanced selective drug release within tumors, resulting in a significant 2.2-fold increase in the tumor-to-blood concentration ratio. This compound is valuable for researching colon cancer and its associated signaling pathways, providing insights into potential therapeutic strategies targeting the TGFβ axis in tumor microenvironments.
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