Fig. 1 · Structure
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TGFβRI-IN-6
Cat. No.
A84880
CAS
2072051-04-6
TGFβRI Inhibitor
TGFβRI-IN-6 is a highly effective inhibitor of TGFβ receptor I, demonstrating an IC50 of 0.55 nM. This compound has shown promise in enhancing anti-tumor immunity, making it a valuable tool for cancer research. Its specific targeting of TGFβRI allows for detailed investigation into the modulation of immune responses in the tumor microenvironment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2072051-04-6 |
| Applications | TGFβRI Inhibitor |
| Formula | C17H10F4N6 |
| Molecular Weight | 374.30 |
| SMILES | FC1=CN=CC=C1NC2=C(C=CN3)C3=NC(C4=NC(C(F)(F)F)=CC=C4)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.